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Results
Exposure to RFR caused decreased body weights of pregnant rats during gestation and lower birth weights in their offspring. However, a few weeks after birth body weights returned to normal and were similar to non-exposed rats. In general, RFR-exposed male rats lived longer than non-exposed rats. The higher survival of exposed males was attributed to a lower severity of a natural, age-related kidney disease typically observed in male rats at the end of these types of studies, which may have been related to the RFR exposure. In both studies (GSM and CDMA),
exposure to RFR in male rats resulted in higher numbers of animals with tumors of the heart and brain. In the GSM study, increased numbers of animals with tumors of the adrenal gland were also observed in exposed males. In both studies, there were tumors that occurred in several organs that we were unable to clearly determine whether these resulted from exposure or were just incidental findings. For the GSM studies, these lesions included tumors of the prostate gland, pituitary gland, and pancreas in males and of the heart in females. For the CDMA studies, these equivocal lesions included tumors of the pituitary gland and liver in males and of the heart, brain, and adrenal gland
of females.
