Message from @Deleted User

Discord ID: 496591930604519425


2018-10-02 00:28:11 UTC  

overdose not as good as correct dose

2018-10-02 00:30:58 UTC  

mmm that seems to be just conjecturing tbh

2018-10-02 03:54:47 UTC  

It is very much a case of diminishing returns

2018-10-02 03:55:12 UTC  

Excess testosterone is converted to estrogen by this lil bastard here

2018-10-02 04:01:48 UTC  

The same general effect is true of most medications

2018-10-02 04:02:28 UTC  

Too much headache meds will actually make your headache worse, too much antidepressants will have the opposite of the intended effect

2018-10-02 07:10:30 UTC  

but in any case, if aromatase converts "excess" test into estradiol, what is the "excess" number? and what prevents it from being higher in blacks?

2018-10-02 07:49:17 UTC  

"In general, the normal range in males is about 270 to 1070 ng/dL with an average level of 679 ng/dL. A normal male testosterone level peaks at about age 20, and then it slowly declines. Testosterone levels above or below the normal range are considered by many to be out of balance. Moreover, some researchers suggest that the healthiest men have testosterone levels between 400 - 600 ng/dL."
It's seemingly ill-defined medically, but there's your answer here, for what would be considered an excess number; over 600
(Source: https://www.medicinenet.com/high_and_low_testosterone_levels_in_men/views.htm# )

Now, there's a degree of conflicting information on whether blacks actually do have higher testosterone, but here's a couple relevant studies;
https://www.ncbi.nlm.nih.gov/m/pubmed/17456570/
https://www.ncbi.nlm.nih.gov/m/pubmed/3455741/

I would come to the conclusion from these that the threshold varies based on more than what has been controlled for, like diet, physical activity, or size

Regardless, however, estrogen is higher in blacks than whites it seems, and testosterone may or may not be higher than in whites as well

2018-10-02 07:49:49 UTC  

mmm interesting

2018-10-02 07:50:28 UTC  

however, on an anecdotal note, i was required by my doctor to measure my test and it was above the normal levels, i remember being over 1000

2018-10-02 07:51:01 UTC  

it's perceptible, i'm hairy, gain muscle fast

2018-10-02 07:51:23 UTC  

but i never had any of the estradiol issues

2018-10-02 07:51:51 UTC  

i'd say that the 1070 cap is the real one then

2018-10-02 07:51:56 UTC  

for a real problem to emerge

2018-10-02 07:53:15 UTC  

Well, to point it out, there's not that prevalent of negative effects of having too much testosterone
15% more than average apparently equates to a doubled risk of prostate cancer, but that's kinda about it, other side effects are evidently rare
But it also doesn't really do anything positive, better, after a certain point, it seems
Yah, that's why I say it probably varies from person to person

2018-10-02 07:54:15 UTC  

It probably depends on how much you actually need

2018-10-02 07:54:23 UTC  

this is a meta one

2018-10-02 07:54:34 UTC  

If you're a layabout, probably will have low T
Lemme look it over rq

2018-10-02 07:59:02 UTC  

I think this right here is a pretty important part to look at

2018-10-02 07:59:06 UTC  

Unadjusted and multivariable-adjusted estradiol concentrations were significantly higher in black than in white men (Table 2); age-adjusted estradiol concentrations did not differ (Fig. 2C).

2018-10-02 08:00:00 UTC  

we should also remember that african-americans were artificially selected during the slavery period, so the biggest and most resilient got to reproduce

2018-10-02 08:00:17 UTC  

just compare african-americans to the actual africans of the western african coast

2018-10-02 08:01:07 UTC  

Yah

2018-10-02 08:01:15 UTC  

I also haven't looked into the uhhh

2018-10-02 08:01:26 UTC  

the yoruba, which iirc is where most of the slaves were taken

2018-10-02 08:01:50 UTC  

Study you were initially looking at, but there may or may not be issues with it, I can check that rq
Ah

2018-10-02 08:06:41 UTC  

Yah, there is an issue of an extremely small sample size, and I didn't see anywhere it controlled for people's tendency to lie _before_ testosterone administration

2018-10-02 08:07:05 UTC  

"The study was approved by the ethics committee of the University Hospital of the University of Bonn. 91 healthy men (age 24.32±2.73(s.d.) years) gave written informed consent prior to inclusion into the study. All subjects were screened to exclude benign prostate hypertrophy, prostate cancer, heart failure, renal failure, hepatic failure, epilepsy or migraine history, and exogenous uptake of cortisone or ACTH. No adverse events occurred."

2018-10-02 08:07:29 UTC  

So the "testosterone reduces urge to lie" thing is a flawed study to begin with

2018-10-02 08:08:18 UTC  

Iirc, a 90 participant study comes out to about a 11% margin of error, which is pretty huge

2018-10-02 15:15:42 UTC  

Pomen#4268 deserted.

2018-10-02 17:26:24 UTC  

<@136281730528051201> marched in.

2018-10-03 00:17:16 UTC  

What in the hell happened to twentyad

2018-10-03 00:20:47 UTC  

Nvm

2018-10-03 02:03:34 UTC  

death i suppose

2018-10-03 14:18:29 UTC  

@Pomen marched in.

2018-10-03 14:19:42 UTC  

Pomen#4268 deserted.

2018-10-03 22:27:29 UTC  

@GanG tussin marched in.

2018-10-04 17:15:42 UTC  

<@492402445419413504> marched in.