Message from @unholybob

Discord ID: 597703340960382976


2019-07-08 08:06:57 UTC  

"CCR5 Δ32 has an (heterozygote) allele frequency of 10% in Europe, and a homozygote frequency of 1%.

Recent research indicates that CCR5 Δ32 enhances cognition and memory. In 2016, researchers showed that removing the CCR5 gene from mice significantly improved their memory.[43] CCR5 is a powerful suppressor for neuronal plasticity, learning, and memory; CCR5 over-activation by viral proteins may contribute to HIV-associated cognitive deficits." - also wikipedia

2019-07-08 08:07:48 UTC  

Hmm

2019-07-08 08:08:09 UTC  

Ah is that that gebe the Chinese edited out from the first gene edit babies?

2019-07-08 08:08:23 UTC  

dunno... probably.

2019-07-08 08:09:08 UTC  

I can remember, that they added some hiv immunity and one article stated it also may have enhanced their cognitive abilities

2019-07-08 08:09:36 UTC  

lol, they're Europeanizing their babies...

2019-07-08 08:10:14 UTC  

But I mean, a 10% allele frequency...
It seems it has some benefits, but it's not so strong that it spreads faster

2019-07-08 08:11:09 UTC  

I'm sure there's some decrease in macrophage activity or something... but, if not, if it's all good, then cool.

2019-07-08 08:11:50 UTC  

For as much immunology work I do, I'm woefully stupid on a lot of things.

2019-07-08 08:12:26 UTC  

I'm a biochemist, though... that's too big for me.

2019-07-08 08:12:37 UTC  

I like molecules.

2019-07-08 08:13:54 UTC  

Hehe cool

2019-07-08 08:14:59 UTC  

So, in general, on one hand, I think all the use of antibiotics etc just accelerated evolution of the bacteria, and there are a lot of multi resistant variants out there

And then comes the std epidemic on top of that size to hookup culture

I think even modern medicine won't be able to cope with that unless we get some nanobots which eliminate all the diseases

2019-07-08 08:15:07 UTC  

Plus, 10% is pretty good for less than 1000 years.

2019-07-08 08:15:49 UTC  

Bacteriophages, man... bacteriophages...

2019-07-08 08:17:34 UTC  

The best antibiotics will be bacteria-specific viruses... but it'll be a genetic arms race between bacteria and viruses, just like (naturally derived) antibiotics were an arms race between bacteria and fungi.

2019-07-08 08:18:36 UTC  

But, there's a serious bioethics question about unleashing a transgenic bacteriophage into the wild...

2019-07-08 08:19:09 UTC  

I doubt it's a problem though.

2019-07-08 08:19:19 UTC  

*creates zombie virus*

2019-07-08 08:19:32 UTC  

"oops"

2019-07-08 08:19:41 UTC  

(j/k)

2019-07-08 08:20:31 UTC  

(unless you're a bacterium)

2019-07-08 08:28:08 UTC  

yeah ok, bateriophages are basically a precursor of nanobots
why creating it ALL when there is actually an "infrastructure" there, which can attack bacteria

2019-07-08 08:28:41 UTC  

but the point remains, it is still an arms race, unless you have the 80, 90 or 99% solution

2019-07-08 08:29:35 UTC  

I mean, I'd be totally ok wiping out mosquitos, I HATE these things
nature will probably find a new equilibrium after they are gone
(probably same with flies) ...

2019-07-08 08:31:06 UTC  

also there are a lot of interesting ethical questions,
I'm ok with humans asserting dominance over their surroundings /nature, that's what we evolved to do (mainly by removing the dangers)

2019-07-08 08:32:11 UTC  

but when we continue playing that game, with transgenic babies/humans ...
and we include more and more other genes, which make us stronger, increase our abilities, etc ...
is there a point, where they basically stop being "human" and are a new species ?

2019-07-08 09:08:34 UTC  

It’s fine. I don’t want to be human anyway.

2019-07-08 09:19:52 UTC  

I'm playing Skyrim as a redgaurd. What do y'all think, imperials or stormcloaks? 🤔

2019-07-08 09:44:48 UTC  

Do you want to weaken the thalmors grip on the empire from within or from the outside?

2019-07-08 09:45:13 UTC  
2019-07-08 09:46:45 UTC  

I actually played as a thalmor agent last playthrough, but this time I'm a stomg independent *KANG* rallying to liberate Skyrim from the white man <:lolz:480186121897377792> but actually I'd say outside 😉

2019-07-08 09:57:43 UTC  

Yo yo yo

2019-07-08 10:00:18 UTC  

I know the solution to skyrim

2019-07-08 10:00:20 UTC  

Just don't play it

2019-07-08 10:01:53 UTC  

Stormcloaks if the outside

2019-07-08 10:02:32 UTC  

Man blackreach is fucking crazy

2019-07-08 10:08:42 UTC  

@Nawalter Jizney congrats on mod status

2019-07-08 10:19:53 UTC  

be a jewish khajiit

2019-07-08 10:20:50 UTC  
2019-07-08 10:21:08 UTC  

<:yay:523032349563158528>