It depends on the circumstances and their previous history/stances. Getting into the whole trans thing, I've always been fairly androgynous/masculine but I am biologically a woman, and I'm fine with that, because I believe God made me a woman for a reason. I believe it's morally wrong to try to change your gender based on feelings - it (to me) means you're basically saying God was wrong about the gender that he created you as, and I don't think that I could see eye to eye with someone who did so. But like I said, totally depends, I would consider all aspects and probably end up voting for them if they were the lesser evil, and the two party system was still in place during that election.
