Message from @sydtko

Discord ID: 660771635665829898


2019-12-29 09:03:14 UTC  
2019-12-29 09:03:23 UTC  

Mosaicism as high as 70%

2019-12-29 09:03:39 UTC  

``` Mosaicism has been reported to be present in as high as 70% of cleavage-stage embryos and 90% of blastocyst-stage embryos derived from in vitro fertilization.[3]```

2019-12-29 09:03:55 UTC  

Meaning even theoretically "identical" twins are not

2019-12-29 09:04:35 UTC  

@Sasha Mosaicism is... very normal without radiation

2019-12-29 09:06:29 UTC  

@AusFox Gene therapy literally entails changing your genetic code of certain cells

2019-12-29 09:06:57 UTC  

@sydtko Changing their expression and surrounding sections of "Gene"

2019-12-29 09:07:10 UTC  

It can chop out the genes...

2019-12-29 09:07:11 UTC  

I have seen no evidence of the actual DNA code itself changing.

2019-12-29 09:07:18 UTC  

just it's state

2019-12-29 09:07:18 UTC  

Chopping out genes entail changing your chromosomes / dna

2019-12-29 09:07:22 UTC  

wat...

2019-12-29 09:07:29 UTC  

WHAT DOES THAT MEAN

2019-12-29 09:07:38 UTC  

"DNA code itself changing"

2019-12-29 09:07:48 UTC  

If you add different base pairs, you agree you're changing

2019-12-29 09:08:26 UTC  

@AusFox A single individual can be chimeric

2019-12-29 09:08:51 UTC  

A single indivdual set of DNA can become chimeric via mutation

2019-12-29 09:08:56 UTC  

So if you chop out certain genes

2019-12-29 09:09:33 UTC  

@AusFox Some amount of your cells DNA will be different...

2019-12-29 09:10:34 UTC  

@AusFox I don't have the numbers on exactly how much DNA is chimeric per each individual

2019-12-29 09:13:45 UTC  

There's something called germline alterations
And ... another type

2019-12-29 09:14:32 UTC  

There's a Mosquito CRISPR experiment that will kill... some species off

2019-12-29 09:14:37 UTC  

They call it a gene drive something?

2019-12-29 09:14:54 UTC  

```Germline mutation is distinct from somatic mutation. ``` Somatic mutation is the other

2019-12-29 09:14:56 UTC  

That will not pass on

2019-12-29 09:15:21 UTC  

You can find lots of pop sci articles about this type of stuff

2019-12-29 09:15:51 UTC  

```Disease vector species

One possible application is to genetically modify mosquitoes and other disease vectors so that they cannot transmit diseases such as malaria and dengue fever. Researchers claimed that by applying the technique to 1% of the wild population of mosquitoes, they could eradicate malaria within a year.[42] ```

2019-12-29 09:16:36 UTC  

That is pretty ridiculous

2019-12-29 09:16:44 UTC  

Oh no

2019-12-29 09:17:02 UTC  

Breast milk could be seen as exploitation of an animal...
But I've never heard someone unironically assert that

2019-12-29 09:17:08 UTC  

So... holy fuck <:pepeLMAO:644901342216847388>

2019-12-29 09:18:09 UTC  

I don't care if you care

2019-12-29 09:18:29 UTC  

Amazin. Then I'm confused why they're talking..
If nobody cares

2019-12-29 09:21:19 UTC  

2019-12-29 09:30:11 UTC  

@AusFox get back