Message from @Deleted User
Discord ID: 525366136917983245
```This diagram shows the biosynthesis of bioactive compounds (indole and certain other derivatives) from tryptophan by bacteria in the gut.[13] Indole is produced from tryptophan by bacteria that express tryptophanase.[13] Clostridium sporogenes metabolizes tryptophan into indole and subsequently 3-indolepropionic acid (IPA),[14] a highly potent neuroprotective antioxidant that scavenges hydroxyl radicals.[13][15][16] IPA binds to the pregnane X receptor (PXR) in intestinal cells, thereby facilitating mucosal homeostasis and barrier function.[13] Following absorption from the intestine and distribution to the brain, IPA confers a neuroprotective effect against cerebral ischemia and Alzheimer’s disease.[13] Lactobacillus species metabolize tryptophan into indole-3-aldehyde (I3A) which acts on the aryl hydrocarbon receptor (AhR) in intestinal immune cells, in turn increasing interleukin-22 (IL-22) production.[13] Indole itself triggers the secretion of glucagon-like peptide-1 (GLP-1) in intestinal L cells and acts as a ligand for AhR.[13] Indole can also be metabolized by the liver into indoxyl sulfate, a compound that is toxic in high concentrations and associated with vascular disease and renal dysfunction.[13] AST-120 (activated charcoal), an intestinal sorbent that is taken by mouth, adsorbs indole, in turn decreasing the concentration of indoxyl sulfate in blood plasma.[13]```
very interesting
Still less degenerate than english with its only one gender
english actually has nominative genitive dative and accusative cases too iirc
unless im remembering a different language
It only has some remains of genitive
But it's still not a real genitive
huh
English still makes the nom/acc distinction for pronouns
It doesn't count
K
>le English is bad
It's not
We never seem to have these conversations in any other language though 🤔
It's just as good as any other language
Some are better for certain uses and for example english is great for songs
It doesn't change the fact that it doesn't have cases so you're statement is kind of out of blue
I know that the first three characters mean "niponese" and if the rest of the runes don't say "is a disgusting and truly barbaric language" then your whole statement is wrong
Lol says the slav
Yeah, so what?
You don't get to play the garbage linguistics game in the amateur league, you guys are in the pros
I'm not really sure if I actually got all what you were saying, but if you meant that slavic languages are great and awesome then I will have to agree
if by biohacking you mean killing people very efficiently, probably someone around here
whats your specific interest in it? im intrigued
🤔
what kind of pills
*dmt*
what substances?
the modafinil doesnt look too healthy but... if you try it, feel free to provide trip report details ^^ i love learning about how certain substances effect physiology.
how'd it make you feel?
interesting.
i'll look up the pharmocology more in-depth later.