Message from @Sock
Discord ID: 570376541238984704
I'm not a chemist lol
just reading the wiki, apparently it was usually used for treating delusional parasitosis
and is apparently quite as effective in treating schizophrenia patients as other antipsychotics
quite funny that it would work on trans too
@Fitzydog I read the study, read it's supporting studies, and about Pimozide itself as I'd never heard of this study.
First, the validity of the study. The study has a sample size of one and has not been repeated, so there is no other supporting evidence.
The patient when on the medication slept for the majority of the day, so naturally the severe lethargy decreased the symptoms present, as the patient's decrease in drive prevented any symptoms to be present, the actions of crossdressing and feeling the need to relieve dysphoria. That does not show any evidence of the symptoms no longer being present, just that the drive to do anything was not, so symptoms could not be verified. The other extraneous factors of the patient having a learning disability also increases the difficulty of verifying any conclusion from the study.
The likelyhood that Pimozide has not been reported to treat gender dysphoria is multiple factors. it is the strongest typical antipsychotic, and it's use was highly experimental. It is a last resort drug and the strongest in it's class, also highly dangerous in moderate doses. Side effects such as permanently decreased motor function and brain damage are possible.
So overall, not a valid conclusion for treatment of the root cause of the patient's gender dysphoria.
It is a thing that may possibly be looked in to, but highly unlikely as the case itself is highly suspect and flawed in multiple ways, not concluding anything
Okay. Is this evidence that there is no medical treatment and that surgery is our best option?
We don't know if there is alternative medical treatment to treating the symptoms of gender dysphoria
`Side effects such as permanently decreased motor function and brain damage are possible.`
severe and unusual side effects are endemic to antipsychotic medications btw
"However, in view of the fact that his concentration appeared impaired and his inappropriate aggressive behaviour also responded to the medication, the possibility that he was suffering from schizophrenia, which like monosymptomatic delusions is also modified by pimozide, cannot be ruled out. Moreover, a pseudotranssexual picture in schizophrenia is not uncommon."
^
ty
I didn't want to write everything out
My hands are cold :/
@Patty You understand what I'm saying with the small sample size though, right?
like if you want to push for it being studies further thats cool
There was only one
studied*
Yes, but it's not conclusive or even suggestive in any way it is a cure
We are not aware of any way to cure the root cause of true gender dysphoria other than transitional therapy
YOU are not aware you mean
Us as humans
As a race
Wrong
As a medical body
Okay but like lets look at it this way.
Then please give your supporting evidence
I've just showed you evidence that there is a possibility for medication to resolve the issue.
Why has no one even tried to investigate this since the 90s? @Patty
I just showed you it is highly suspect and the dysphoria may have been brought on by extraneous factors
We have one study on one person where the authors weren't even super on board with it proving anything, only suggesting maybe it should be tested more. On the other side we have 52 studies with far more than one person saying transition has positive results
^
Yes
You think we just try once, find the magic cure, and that's that?
There was _nothing_ to suggest it would work
Could it be? Highly unlikely but possible
Then explain to me why the case I showed you, is the MOST RECENT one done
Because nobody wants to throw extremely strong actually brain damaging medications at their patients
When there is 0 evidence