donnie.blanko

Discord ID: 670857733976752148


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2020-01-29 02:16:54 UTC [Outer Heaven #join-log]  

2020-01-31 05:20:33 UTC [Outer Heaven #general-serious]  

Corona virus and ACE2 Blockers as infection management

"Previous reports identified ACE2 as the receptor for the severe acute respiratory syndrome (SARS) coronavirus"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229671/

If this is also true for the 2019-nCoV virus, being largely similar to the SARS virus from what we know then.

https://en.wikipedia.org/wiki/Angiotensin_II_receptor_blocker#Mechanism_of_action

we read on to find that compounds which block ACE2 are not uncommon at all. This common blood pressure medication looks like its 99% effective at binding to ACE2 receptors, many other options are available.

https://en.wikipedia.org/wiki/Candesartan

If this is all true, then this could potentially be used as a treatment, once infection is identified, from progressing to the point where viral load causes a ketonic storm, organ failure, and such as well as prevent spread as the virus finds it difficult to find ACE2 binding sites.

Additionally, combine the inhibitors with things that upregulate/strengthen glutathione activity as well.

https://www.ncbi.nlm.nih.gov/pubmed/23089304

"It is important to note that the increases in the levels of pro-inflammatory cytokines are not only detrimental to the host due to the sequel that follow such as fever and cachexia, but also due to the alteration in the functions of immune cells. The additional protective effects of GSH are evident after sequel that follows the depletion of this antioxidant."

eat lots of fat to raise cholesterol

https://academic.oup.com/qjmed/article/96/12/927/1533176

I am not a doctor.

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